Movie-Watching Functional MRI for Mapping Brain Function in Neurosurgical Patients

This research will compare a new type of functional MRI (fMRI) called naturalistic viewing (also called movie watching) to standard clinical fMRI techniques. Standard clinical fMRI currently uses multiple tasks such as reading and responding to words or sentences to determine which areas of the brain are responsible for language. Surgeons can use this information to help plan brain surgeries. This research will help determine if the movie-watching fMRI is equivalent or better than the standard task-based fMRI. If so, it could be useful for planning patients' surgeries in the future, without the need for multiple tasks.

NCT Number	NCT07650994
Lead Sponsor	Brigham and Women's Hospital Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions	Glioma, Brain Tumor Adult
Enrollment	90 participants
Start Date	2026-09-01
Primary Completion	2029-03-31 (estimated)
Study Completion	2029-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-22