Pulmonary Hypertension (PH) Biorepository for Translational Research

Background: Pulmonary hypertension (PH) is high blood pressure in the blood vessels of the lungs. It can lead to heart failure and death if not treated. Researchers want to create a repository of blood samples and health information collected from people with PH. They hope to use this information to find better ways to diagnose and treat PH. Objective: To collect blood samples and health information from people suspected of or diagnosed with PH. Eligibility: People aged 18 years and older who have or may have PH. Design: Researchers will collect information from participants medical records. Participants will have blood drawn from a vein. About 3 tablespoons will be collected during the study visit. The visit will last about 1 hour. Participants may choose to provide new blood samples at follow-up visits. Updated medical information may also be collected. Participants may continue to participate as long as the study is ongoing. Participants may opt out of providing new blood samples but remain in the study. All study samples will be stored at the National Institutes of Health. Health information will be stored in secure databases.

NCT Number	NCT07647549
Lead Sponsor	National Institutes of Health Clinical Center (CC)
Conditions	Pulmonary Hypertension
Enrollment	1,000 participants
Start Date	2026-08-19
Primary Completion	2036-06-01 (estimated)
Study Completion	2036-06-01 (estimated)
Updated on ClinicalTrials.gov	2026-08-14