Using Breath Tests to Study Gut Sulfur Changes During Dietary Therapy

This study aims to test whether a short liquid-based diet, followed by a low-sulfur eating plan, is safe, manageable, and helpful for people with mild to moderate ulcerative colitis. Investigators want to see if this approach can improve gut health, lower inflammation, and reduce symptoms. Investigators will also test breath samples as an easy, non-invasive way to track gut bacteria activity and disease changes. Investigators believe this diet plan can reduce harmful gut bacteria that produce irritating sulfur compounds, leading to better gut health and measurable improvements that can be detected through breath testing.

NCT Number	NCT07640659
Lead Sponsor	University of British Columbia Collaborators: University of Calgary
Conditions	Ulcerative Colitis (UC)
Enrollment	45 participants
Start Date	2026-06-01
Primary Completion	2029-03-01 (estimated)
Study Completion	2029-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-11