Evaluation of [¹⁸F]MODAG-009 PET Imaging in Synucleinopathies

This is a single-center, open-label clinical study designed to evaluate the imaging characteristics and safety of \[¹⁸F\]MODAG-009 in participants with Parkinson's disease (PD), Multiple system atrophy (MSA), and Healthy controls (HC). Approximately 13 participants will be enrolled in this study. Each participant will receive a single intravenous injection of \[¹⁸F\]MODAG-009, followed by PET imaging using the investigational United Imaging NeuroEXPLORER (NX) camera.

NCT Number	NCT07640555
Lead Sponsor	MODAG GmbH Collaborators: XingImaging, LLC, Institute for Neurodegenerative Disorders
Conditions	Multiple System Atrophy (MSA), Healthy Adult, Parkinson Disease
Enrollment	13 participants
Start Date	2026-05-13
Primary Completion	2027-05 (estimated)
Study Completion	2027-05 (estimated)
Updated on ClinicalTrials.gov	2026-06-10