PRehabilitation Intervention to Modify Eating for Breast Cancer Patients (PRIME)

This single-arm pilot study evaluates the feasibility and acceptability of a 4-week Mediterranean diet-based feeding intervention as nutritional prehabilitation for newly diagnosed, treatment-naïve breast cancer patients prior to surgery. All meals are provided to participants. Secondary aims include assessing changes in body composition, metabolic biomarkers, inflammation, gut microbiome composition, patient-reported outcomes, and clinician-reported surgical recovery metrics.

NCT Number	NCT07638150
Lead Sponsor	H. Lee Moffitt Cancer Center and Research Institute
Conditions	Breast Cancer
Enrollment	20 participants
Start Date	2026-08
Primary Completion	2027-04 (estimated)
Study Completion	2027-04 (estimated)
Updated on ClinicalTrials.gov	2026-06-10