"Balance, Gait, and Motion Analysis in Multiple Sclerosis"

The goal of this observational cross-sectional study is to investigate the relationship between functional measures of balance and gait and objective kinetic and kinematic parameters in people with Multiple Sclerosis (MS). The main questions it aims to answer are: i) What is the relationship between kinetic and kinematic gait and balance parameters measured using the Vicon motion analysis system and performance on clinical functional assessments in people with Multiple Sclerosis? ii) Which biomechanical parameters are most strongly associated with functional balance, gait, and physical performance outcomes? Participants will attend a single laboratory-based assessment session. During this session, they will undergo biomechanical gait and balance analysis using the Vicon motion capture system, complete functional assessments of balance, gait, and physical performance, complete questionnaires assessing fear of falling and fatigue, and undergo assessment of lower-limb spasticity.

NCT Number	NCT07630311
Lead Sponsor	University of Patras Collaborators: University Hospital, Ioannina
Conditions	Multiple Sclerosis, Gait Disorders, Neurologic, Postural Balance, Motion Analysis, Biomechanics, Kinetics, Kinematics, Physiotherapy +2 more
Enrollment	40 participants
Start Date	2025-09-01
Primary Completion	2026-02-28 (estimated)
Study Completion	2026-08-30 (estimated)
Updated on ClinicalTrials.gov	2026-06-24