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Neoadjuvant Radiotherapy Combined With NALIRIFOX and Adebrelimab in pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Randomized, Phase II Clinical Trial

Name: Neoadjuvant Radiotherapy Combined With NALIRIFOX and Adebrelimab in pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Randomized, Phase II Clinical Trial — clinical trial record (NCT07622771)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhasePhase 2

SponsorSun Yat-sen University

Started2026-05-26

View on ClinicalTrials.gov ↗

Amendment history

2026-09-18

Recruitment opened

Sun Yat-sen University

609 trials monitored

See 13 trials at risk

Colorectal Cancer

2,904 trials monitored

See 127 trials at risk

To explore the efficacy and safety of radiotherapy combined with Adebrelimab and NALIRIFOX in patients with pMMR/MSS locally advanced rectal cancer

Trial Details

NCT Number	NCT07622771
Lead Sponsor	Sun Yat-sen University
Conditions	Rectal Cancers
Enrollment	84 participants
Start Date	2026-05-26
Primary Completion	2028-06-30 (estimated)
Study Completion	2032-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-09-17