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Sevoflurane vs Propofol Anesthesia in Obese Patients Undergoing Lumbar Surgery

StatusRecruiting
PhaseNot applicable
Started
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Record status
This record was last updated May 28, 2026 (before its estimated June 15, 2026 completion). Its status may not reflect the trial's current state.

Record History

  1. Study First Submitted
Ataturk University
176 trials monitored
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Obesity
3,874 trials monitored
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This randomized, single-center, single-masked clinical trial aims to compare the immunomodulatory effects of sevoflurane-based inhalational anesthesia and propofol-based total intravenous anesthesia in obese patients undergoing elective lumbar instrumentation surgery. Seventy patients will be randomized into two groups: a propofol group and a sevoflurane group. Blood samples will be collected preoperatively, at postoperative 6 hours, and at postoperative 24 hours. Pentraxin-3 and serum amyloid A levels will be evaluated as primary inflammatory biomarkers together with IL-6, TNF-α, CRP, glucose, and complete blood count parameters.
Trial Details
NCT Number NCT07611240
Lead Sponsor Ataturk University
Conditions
(from sponsor)		 Obesity & Overweight, Lumbar Spine Surgery
Related terms Obesity, Overweight
Enrollment 70 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov