Clinical Trial

Periodontal Inflammation and Epigenetics in Obese Individuals

Not Yet Recruiting
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Summary
The goal of this study is to investigate the long-term changes in host epigenetic modifications in obese individuals with periodontitis. The aims of the study are: • To monitor longitudinal changes in host epigenetic modifiers following non-surgical periodontal therapy in periodontitis patients Study subjects would be categorized into two groups, non-obese with periodontitis, and obese with periodontitis. The study will primarily evaluate changes among these groups cross-sectionally, then longitudinally following non-surgical periodontal therapy (deep cleaning) to determine if any changes occur with treatment.
Trial Details
NCT Number NCT07610902
Lead Sponsor Louisiana State University Health Sciences Center in New Orleans
Conditions Obesity, Periodontitis
Enrollment 40 participants
Start Date 2026-05-25
Primary Completion 2026-12-30 (estimated)
Study Completion 2026-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-28