Clinical Trial

BEYOND Study: A Multicentre, Prospective, Observational Study of Real-world Treatment Patterns and Outcomes of Trastuzumab Deruxtecan in Patients With HR Positive, HER2-low or Ultra-low Metastatic Breast Cancer Previously Treated With Endocrine Therapy

Study acronym: BEYOND
Recruiting
View on ClinicalTrials.gov →
Summary
BEYOND study is designed to generate the first real-world data from GCC countries on the patient characteristics, treatment patterns, survival outcomes, and safety of T-DXd in patients with HRpositive,HER2-low or HER2-ultralow mBC previously treated with ET. The evidence generated will help to optimise treatment strategies, inform clinical guidelines, and ultimately improve outcomes for patients with mBC across the region.
Protocol Amendment History 4 changes
critical Recruitment opened 2026-08-11
notable Trial sites expanded: 2 -> 9 locations 2026-08-11
notable Primary completion moved earlier: 2029-06-30 -> 2029-03-31 2026-08-11
minor Completion moved earlier: 2029-06-30 -> 2029-03-31 2026-08-11
Trial Details
NCT Number NCT07597993
Lead Sponsor AstraZeneca
Conditions Breast Cancer
Enrollment 109 participants
Start Date 2026-07-12
Primary Completion 2029-03-31 (estimated)
Study Completion 2029-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-10