Clinical Trial

Use of Liraglutide in Children Aged 6 to 12 Years With Severe Obesity

Active, Not Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
This randomized controlled trial evaluates the efficacy, safety, metabolic, and cardiovascular effects of liraglutide in children aged 6 to 12 years with severe obesity. Participants are randomized to receive liraglutide plus lifestyle intervention or lifestyle intervention alone for 6 months. In addition to primary outcomes related to weight loss and metabolic improvement, a predefined subgroup analysis evaluates cardiovascular function in participants receiving liraglutide using advanced echocardiographic techniques, including speckle-tracking-derived myocardial deformation parameters.
Trial Details
NCT Number NCT07590219
Lead Sponsor University of Sao Paulo General Hospital
Conditions Severe Obesity, Cardiovascular Function, Liraglutide, Childhood Obesity, Echocardiography, Speckle Tracking
Enrollment 30 participants
Start Date 2024-03-30
Primary Completion 2027-04 (estimated)
Study Completion 2028-04 (estimated)
Updated on ClinicalTrials.gov 2026-05-15