Clinical Trial

Effect of Finerenone on Myocardial Fibrosis and Cardiac Function in HFmrEF/HFpEF Patients

Study acronym: FINE-FOCUS
Not Yet Recruiting Phase 4
View on ClinicalTrials.gov →
Summary
FINE-FOCUS study is a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial to evaluate the effect of Finerenone versus placebo on myocardial fibrosis and cardiac structure/function as assessed by cardiac magnetic resonance (CMR) in symptomatic heart failure patients with a left ventricular ejection fraction (LVEF) ≥40%. A sub-study will include 18F-FAPI-PET/CT imaging to evaluate the effect of finerenone on myocardial fibrosis.
Trial Details
NCT Number NCT07583173
Lead Sponsor China National Center for Cardiovascular Diseases
Conditions Heart Failure
Enrollment 104 participants
Start Date 2026-05-15
Primary Completion 2027-10-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-05-13