Clinical Trial

Drug-Drug Interaction Study of Atumelnant in Healthy Participants

Active, Not Recruiting Phase 1
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Summary
This study aims to evaluate the impact of strong CYP3A4 induction on the pharmacokinetics (PK) of atumelnant, as well as the effect of atumelnant on CYP3A4, P-gp, and MATE1/2-K substrates in healthy participants.
Protocol Amendment History 1 change
critical Trial status changed: Recruiting → Active, Not Recruiting 2026-07-07
Trial Details
NCT Number NCT07570082
Lead Sponsor Crinetics Pharmaceuticals Inc.
Conditions Healthy Volunteers
Enrollment 46 participants
Start Date 2026-05-28
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-07-06