Sponsor pipeline

Crinetics Pharmaceuticals Inc. clinical trial pipeline

Get alerts when Crinetics Pharmaceuticals Inc.'s trials change

6 active trials 5 recruiting 3 Phase 3 10 changes in 30 days

Data updated daily from ClinicalTrials.gov, last refresh 2026-08-28

What changed in the last 30 days

2026-07-30
critical
Trial terminated
Trial terminated: The study was stopped early for business reasons (not due to changes in the benefits or risks of paltusotine).
Primary completion moved earlier: 2028-03-31 → 2026-06-30
Completion moved earlier: 2028-03-31 → 2026-06-30
NCT04261712 A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of… · Phase 2
2026-08-20
notable
Enrollment closed, study ongoing
NCT05804669 A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome · Phase 1/2
2026-08-20
notable
Trial completed
Primary completion moved earlier: 2026-12-31 → 2026-06-30
Completion moved earlier: 2026-12-31 → 2026-07-30
NCT07570082 Drug-Drug Interaction Study of Atumelnant in Healthy Participants · Phase 1
2026-08-13
minor
Trial sites expanded: 55 → 63 locations
NCT07144163 A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia · Phase 3
2026-08-05
minor
Trial sites expanded: 51 → 67 locations
NCT07087054 Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen · Phase 3

Active trials by phase

Phase 1/2
2
Phase 2
1
Phase 2/3
1
Phase 3
2

Active trials

NCT IDTitleConditionStatusUpdated
Phase 3
NCT07144163 A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia Congenital Adrenal Hyperplasia Recruiting 2026-08-12
NCT07087054 Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen Carcinoid Syndrome Recruiting 2026-08-04
Phase 2/3
NCT07159841 A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH) Congenital Adrenal Hyperplasia Recruiting 2026-08-12
Phase 2
NCT06712823 An Extension Study to Evaluate Safety and Efficacy of Atumelnant in Participants With… Congenital Adrenal Hyperplasia Recruiting 2026-06-29
Phase 1/2
NCT07129252 A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With… SST2-positive Neuroendocrine Neoplasms Recruiting 2026-07-31
NCT05804669 A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome Cushing Syndrome Active, Not Recruiting 2026-08-19
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