Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07566312 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Study of QL Analgesic Response and Extent

Study acronym: SQUARE
StatusNot Yet Recruiting
PhasePhase 4
Started2027-01
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 4 months later Nov 2026 → Apr 2027
See other at-risk trials from Duke University

Amendment history

2026-07-07
notable
Study Status v1
Primary completion pushed: 2026-11 → 2027-04
Completion pushed: 2026-12 → 2027-04
Start date2026-05→2027-01
2026-04-29
minor
Original filing
455 trials monitored
See 53 trials at risk
A total of 14-18 healthy volunteers will be included. There will be three different procedure days, separated by at least one week. On each visit, the subjects will receive a QL block, according to the randomization process. Each volunteer will undergo pre-procedure screening on the first visit. The blocks will be performed on the same side, by the same anesthesiologist, with at least one week between each block. An anterior QL block will be administered on one day, a posterior QL block on another, and a lateral QL block on the third. The order will be randomized, and both the subject and the research team member assessing the block will be blinded. To compare the dermatomal sensory block distribution, the investigators will use detailed mapping with pinprick, cold, and heat stimuli. A handheld dynamometric assessment of lower extremity strength. The testing will be performed 60 to 90 minutes after performance of the blocks.
Trial Details
NCT Number NCT07566312
Lead Sponsor Duke University
Conditions Acute Pain, Postoperative Pain, Regional Anesthesia Block
Enrollment 25 participants
Start Date 2027-01
Primary Completion 2027-04 (estimated)
Study Completion 2027-04 (estimated)
Updated on ClinicalTrials.gov 2026-07-08