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Comparing Two Different Boost Approaches in Radiation Therapy for People With Prostate Cancer

StatusRecruiting
PhasePhase 3
Started2026-04-16
View on ClinicalTrials.gov ↗

Amendment history

2026-06-15
minor
Study Status, Eligibility v2
Eligibility criteria+96 characters
[...] 4+3) cancer with all pattern 4 found only in the MRI target; systematic biopsy pattern 4 that is concordant with MRI target per investigator is permissible Gland size ≤ 80 cc Prostate MRI < rT3b disease IPSS < 20 No [...]
2026-05-06
minor
Study Status, Study Description, Eligibility v1
Re-verified, no change to tracked fields
2026-04-17
minor
Original filing
In this study the investigators will find out whether the use of a new type of boost approach called irreversible electroporation (IRE) is as effective as the standard boost approach of radiation therapy for participants with intermediate-risk prostate cancer receiving standard stereotactic body radiotherapy (SBRT).
Trial Details
NCT Number NCT07548164
Lead Sponsor Memorial Sloan Kettering Cancer Center
Collaborators: Angiodynamics, Inc.
Conditions Prostate Cancer
Enrollment 224 participants
Start Date 2026-04-16
Primary Completion 2029-04-16 (estimated)
Study Completion 2029-04-16 (estimated)
Updated on ClinicalTrials.gov 2026-09-18