Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery

Sleep quality is a key physiological factor influencing immune function, inflammatory response, and pain perception. This prospective observational study aims to evaluate whether preoperative sleep quality predicts postoperative inflammation, pain severity, and analgesic consumption in patients undergoing elective breast cancer surgery. Preoperative sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). Systemic inflammatory response will be evaluated using the Systemic Immune-Inflammation Index (SII), calculated from routine hematological parameters. Postoperative pain will be assessed using the Visual Analog Scale (VAS), and analgesic consumption will be recorded within the first 24 hours. The study aims to determine whether poor sleep quality is associated with increased inflammatory response, higher pain scores, and greater analgesic requirement.

NCT Number	NCT07547774
Lead Sponsor	Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Conditions	Breast Cancer, Postoperative Pain, Inflammation
Enrollment	150 participants
Start Date	2026-04-01
Primary Completion	2026-07-01 (estimated)
Study Completion	2026-07-15 (estimated)
Updated on ClinicalTrials.gov	2026-04-30