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A Single-arm Phase II Clinical Study of Camrelizumab Combined With Long-course Chemoradiotherapy for Total Neoadjuvant Therapy in Locally Advanced Low pMMR/MSS Rectal Cancer

StatusRecruiting
PhasePhase 2
Started2026-02-01
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In pMMR/MSS locally advanced rectal cancer, can the innovative "chemo-immunotherapy induction + LCRT + chemo-immunotherapy consolidation" approach significantly improve the complete response rate and create opportunities for organ preservation?
Trial Details
NCT Number NCT07527026
Lead Sponsor Chinese PLA General Hospital
Conditions Locally Advanced Rectal Cancer
Enrollment 44 participants
Start Date 2026-02-01
Primary Completion 2028-02-01 (estimated)
Study Completion 2029-02-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-14