Dosing and Deployment Trial: A Home-based Optokinetic Treatment

Several interventions exist for remediation of spatial neglect, but they have mixed evidence. Optokinetic stimulation is a bottom-up intervention; in other words, it is a stimulus-driven process, with Level A (strongest) evidence, and is recommended in clinical practice guidelines such as the American Heart Association's stroke guidelines. The studies currently published all use varing doses (number of sessions a week), did not assess the impact on mobility and risk of falls, and have not been implemented in the home setting. It is imperative to understand how to successfully implement this intervention at home, and learn how it will impact mobility in order to better support a large population of individuals living with chronic spatial neglect and who face barriers to accessing care because they require caregiver support to leave the home. This will be done using both qualitative and quantitative methods.

NCT Number	NCT07519317
Lead Sponsor	Duke University
Conditions	Spatial Neglect
Enrollment	90 participants
Start Date	2027-01-04
Primary Completion	2028-02-01 (estimated)
Study Completion	2028-06-16 (estimated)
Updated on ClinicalTrials.gov	2026-06-25