Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07518901 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Nanozymes in Endodontics

StatusEnrolling by Invitation
PhasePhase 4
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 11 months later Jun 2027 → Jun 2028
See other at-risk trials from University of Pennsylvania

Record History

  1. Primary completion pushed from Jun 2027 to Jun 2028 Enrolling by invitation only · Start date: Jun 2026 to Aug 24, 2026 · Site contact updatedv2 Show 3 more changesShow less
    • Enrolling by invitation only
    • Start date: Jun 2026 to Aug 24, 2026
    • Site contact updated
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The antimicrobial efficacy and healing potential of clinically approved ferumoxytol nanozymes versus the standard 3% NaOCl irrigant will be evaluated in adults undergoing endodontic treatment. Building on prior protocols that demonstrated ferumoxytol nanozymes antimicrobial activity as a root canal irrigant, ferumoxytol solution will be applied topically, assessment of clinical and radiographical findings will determine its potential as a novel disinfection and its long-term outcome.
Trial Details
NCT Number NCT07518901
Lead Sponsor University of Pennsylvania
Conditions Apical Periodontitis, Endodontic Disease, Root Canal Infection
Enrollment 72 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov