Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07509307 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

Name: AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain — clinical trial record (NCT07509307)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: AMAZE 6

StatusRecruiting

PhasePhase 3

SponsorNovo Nordisk A/S

Started2026-04-20

View on ClinicalTrials.gov ↗

This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111, (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.

Amendment history 3 changes detected by DataLookout

2026-05-16

Recruitment opened

2026-05-16

Trial sites expanded: 78 → 81 locations

2026-05-16

Primary completion pushed: 2028-06-19 → 2028-08-14

Trial Details

NCT Number	NCT07509307
Lead Sponsor	Novo Nordisk A/S
Conditions	Obesity, Overweight, Osteoarthritis, Knee
Enrollment	400 participants
Start Date	2026-04-20
Primary Completion	2028-08-14 (estimated)
Study Completion	2028-08-14 (estimated)
Updated on ClinicalTrials.gov	2026-08-17