Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation

Ulcerative colitis (UC) is a disease that causes long-term inflammation in the digestive tract, and many people with this condition require surgery to remove the colon and create a new J-pouch for stool. Some patients develop a problem called pouchitis, where this pouch becomes inflamed. Current treatments are limited, and there are no known ways to prevent pouchitis from starting. This study is being done to find out if a natural mineral supplement called Aquamin® can help reduce inflammation and protect the gut lining in people with a J-pouch, and may reduce the risk of pouchitis. By understanding whether Aquamin® is safe and helpful, the study team hopes to find a new and better way to prevent inflammation and improve the long-term health of people with UC.

NCT Number	NCT07501078
Lead Sponsor	Muhammad N Aslam, MD Collaborators: Crohn's and Colitis Foundation
Conditions	Ulcerative Colitis, Ileal Pouch
Enrollment	52 participants
Start Date	2026-07
Primary Completion	2029-05 (estimated)
Study Completion	2029-05 (estimated)
Updated on ClinicalTrials.gov	2026-06-29