MIMICC Study in Patients With Colorectal Cancer

This multicenter prospective interventional study will evaluate stool and saliva microRNA expression and microbiome composition in patients with histologically confirmed colon or rectal cancer during key phases of the diagnostic and therapeutic pathway. The study aims to confirm and refine molecular signatures associated with colorectal cancer, assess the diagnostic and prognostic potential of salivary biomarkers, and characterize dynamic molecular changes during treatment and follow-up

NCT Number	NCT07494201
Lead Sponsor	Fondazione del Piemonte per l'Oncologia
Conditions	Colorectal Cancer, Colon Cancer, Rectal Cancers
Enrollment	2,500 participants
Start Date	2025-09-15
Primary Completion	2027-06-30 (estimated)
Study Completion	2028-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-03-27