Risk of Hydroceles Following Pyeloplasty

This population-based study will use provincial health administrative data to examine the risk of hospital admission for hydrocelectomy among males who underwent laparoscopic pyeloplasty, compared with males from the general population with similar baseline health characteristics. We will use health administrative data from Ontario, Canada, to identify males who had a laparoscopic pyeloplasty between 2002 and 2024. We will calculate a propensity score based on sociodemographic characteristics, comorbidities, and health care utilization. We will then match laparoscopic pyeloplasty males to non-pyeloplasty male controls (1:10) based on propensity score, age, and index date. The primary outcome is hospital admission for hydrocelectomy. The secondary outcomes are a hydrocele diagnosis and receipt of a scrotal ultrasound.

NCT Number	NCT07483463
Lead Sponsor	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Conditions	Hydrocele, Hydrocelectomy, Pyeloplasty
Enrollment	15,000 participants
Start Date	2002-04-01
Primary Completion	2024-03-31 (estimated)
Study Completion	2025-03-31 (estimated)
Updated on ClinicalTrials.gov	2026-06-09