A Phase II Trial Evaluating Radiation Boost to Painful Spinal Metastases

Spine SBRT is considered a standard of care for the treatment of spinal metastases. Compared to conventional radiation therapy, spine SBRT delivers high doses of radiation to the affected areas to the spinal metastases. This study is interested in seeing whether an additional 'boost' of radiation, delivered to the affected area in the spine, will result in better long-term control of the tumor; help reduce pain; and reduce long-term side effects of radiation therapy.

NCT Number	NCT07478289
Lead Sponsor	Sunnybrook Health Sciences Centre
Conditions	Spine Metastasis
Enrollment	108 participants
Start Date	2026-04
Primary Completion	2029-12 (estimated)
Study Completion	2031-12 (estimated)
Updated on ClinicalTrials.gov	2026-03-17