Clinical Trial

Ph 2 Elacestrant in ER Positive Uterine Sarcomas

Recruiting Phase 2
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Summary
This study is to evaluate the efficacy and safety of elacestrant, in participants with advanced estrogen receptor (ER)-positive uterine sarcomas. The name of the study drug involved in this research study is: -Elacestrant (a type of selective estrogen receptor degrader)
Protocol Amendment History 1 change
critical Recruitment opened 2026-04-22
Trial Details
NCT Number NCT07467772
Lead Sponsor Dana-Farber Cancer Institute
Collaborators: Stemline Therapeutics, Inc.
Conditions Uterine Sarcoma, Uterine Leiomyosarcoma, Endometrial Stromal Sarcoma, ESS, Perivascular Epithelioid Cell Tumors, Uterine Adenosarcoma, Uterine PEComa, Estrogen Receptor Positive Tumor +1 more
Enrollment 30 participants
Start Date 2026-03-25
Primary Completion 2027-07 (estimated)
Study Completion 2028-04 (estimated)
Updated on ClinicalTrials.gov 2026-05-22