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A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma

Name: A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma — clinical trial record (NCT07456033)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: MODIFY

StatusRecruiting

PhasePhase 3

SponsorGlaxoSmithKline

Started2026-03-13

View on ClinicalTrials.gov ↗

The aim of this study is to evaluate the efficacy of depemokimab administered as an adjunctive therapy, in participants with Type 2 asthma at risk of exacerbations compared to the guideline recommended standard of care (SoC).

Amendment history 5 changes detected by DataLookout

2026-08-18

Trial sites expanded: 8 → 17 locations

2026-08-18

Primary completion pushed: 2030-07-08 → 2030-09-23

2026-08-18

Completion pushed: 2030-07-08 → 2030-09-23

2026-06-26

Recruitment opened

2026-06-26

Trial sites expanded: 0 → 8 locations

Trial Details

NCT Number	NCT07456033
Lead Sponsor	GlaxoSmithKline
Conditions	Asthma
Enrollment	456 participants
Start Date	2026-03-13
Primary Completion	2030-09-23 (estimated)
Study Completion	2030-09-23 (estimated)
Updated on ClinicalTrials.gov	2026-08-17