Clinical Trial

Ted Rogers Understanding of Exacerbations in Heart Failure 2: Monitor

Study acronym: TRUE-HF 2
Recruiting
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Summary
Heart Failure (HF) is a complex disease associated with the highest burden of cost to the healthcare system. The cardiopulmonary exercise test (CPET) is instrumental in determining the prognosis of patients with HF. This multicentre study will validate whether aggregate biometric data from the Apple Watch combined with demographic, cardiac, and biomarker testing can improve our ability to predict heart failure outcomes among a diverse outpatient HF population.
Protocol Amendment History 2 changes
critical Recruitment opened 2026-07-07
critical Primary endpoint(s) modified 2026-07-07
Trial Details
NCT Number NCT07447908
Lead Sponsor University Health Network, Toronto
Collaborators: Canadian Institutes of Health Research (CIHR)
Conditions Heart Failure, Heart Failure - NYHA II - IV, Heart Failure Patients, Cardiopulmonary Exercise Test, Apple Watch
Enrollment 360 participants
Start Date 2026-06-16
Primary Completion 2029-09 (estimated)
Study Completion 2029-09 (estimated)
Updated on ClinicalTrials.gov 2026-07-06