Clinical Trial

Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?

Not Yet Recruiting
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Summary
This study will test whether biological sex influences how the body responds to circadian misalignment-a mismatch between the internal body clock and the timing of sleep and eating (as can occur with shift work or jet lag). Researchers will examine how circadian misalignment affects appetite regulation (hunger/fullness) and glucose metabolism (blood sugar control), and whether these effects differ between females and males. Findings may help inform more personalized shift work schedules and targeted strategies to reduce metabolic health risks and sex-related differences in clinical care.
Trial Details
NCT Number NCT07441265
Lead Sponsor Brigham and Women's Hospital
Conditions Circadian Misalignment, Sex Differences
Enrollment 36 participants
Start Date 2026-10-01
Primary Completion 2030-09-30 (estimated)
Study Completion 2030-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-02-27