Guardant Shield Colorectal Cancer Screening

The purpose of this research is to identify individuals overdue for colon cancer screening and send them a reminder to complete their screening, which includes standard of care colonoscopy or stool-based testing. The investigators are randomizing patients (like a flip of a coin) to either receive the standard reminder by mail/email or to receive the standard reminder and have the option to provide a blood sample for screening (ShieldTM by Guardant).

NCT Number	NCT07436637
Lead Sponsor	University of Miami Collaborators: Guardant Health, Inc.
Conditions	Colorectal Cancer
Enrollment	500 participants
Start Date	2026-07-22
Primary Completion	2027-04-01 (estimated)
Study Completion	2027-04-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-27