Skin Color Matching in Head and Neck Reconstructive Surgery

This study will examine whether cutaneous reconstruction with RECELL® atop de-epithelialized tissue provides better skin color matching than standard grafting methods. The goal is to compare color match, healing, and patient satisfaction across three reconstruction techniques. Color matching will be assessed using colorimeter-based ΔE00 measurements at set postoperative intervals. All patients will receive the same intervention.

NCT Number	NCT07431099
Lead Sponsor	Yale University
Conditions	Head and Neck Cancer, Head and Neck Trauma
Enrollment	20 participants
Start Date	2026-05-20
Primary Completion	2028-09 (estimated)
Study Completion	2028-09 (estimated)
Updated on ClinicalTrials.gov	2026-05-29