Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US

This study will test olatorepatide (study drug) to determine how safe and effective this drug is and how easily your body can accept this drug without causing side effects, as well as how the drug is processed in the body by participants with overweight or obesity. The study will test how safe and effective the study drug works compared to placebo in people who are overweight or obese but do not have diabetes. The study is looking at: * What side effects the study drug might cause * How much the study drug is in the blood at different times * How well the study drug works * If the body makes antibodies to the study drug as this may cause the study drug to not work as well

NCT Number	NCT07431086
Lead Sponsor	Regeneron Pharmaceuticals
Conditions	Overweight or Obesity
Enrollment	120 participants
Start Date	2026-03-16
Primary Completion	2026-11-13 (estimated)
Study Completion	2026-12-18 (estimated)
Updated on ClinicalTrials.gov	2026-06-17