Inherited and Environmental Risks Acting on Body Weight

The goal of this research is to investigate genetic and environmental factors that contribute to obesity through brain inflammation. The main questions are 1) if identical twins, who differ in food consumption habits, have differences in adiposity markers and brain inflammation and 2) if signs of brain inflammation in response to a specific diet is modified by genetics.

NCT Number	NCT07430852
Lead Sponsor	University of Washington Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions	Genetics, Obesity
Enrollment	110 participants
Start Date	2026-09-01
Primary Completion	2029-11-01 (estimated)
Study Completion	2030-04-30 (estimated)
Updated on ClinicalTrials.gov	2026-02-24