Clinical Trial

A Study of Trastuzumab Deruxtecan in People With Non-Small Cell Lung Cancer

Recruiting Phase 2
View on ClinicalTrials.gov →
Summary
The purpose of this study is to find out how many people with HER2-amplified or HER2-mutated non-small cell lung cancer (NSCLC) experience a decrease in tumor viability when they receive trastuzumab deruxtecan before routine surgery to remove tumors.
Trial Details
NCT Number NCT07428044
Lead Sponsor Memorial Sloan Kettering Cancer Center
Collaborators: AstraZeneca
Conditions Non-Small Cell Lung Cancer, Non-small Cell Lung Cancer Stage II, Non-Small Cell Lung Cancer Stage IIIA, Non-Small Cell Lung Cancer Stage IIIB
Enrollment 14 participants
Start Date 2026-02-13
Primary Completion 2027-02-13 (estimated)
Study Completion 2027-02-13 (estimated)
Updated on ClinicalTrials.gov 2026-02-23