Clinical Trial

Data-driven Clustering in Hemorrhoid Surgery: Retrospective Monocentric Study for the Identification of Clinical Phenotypes

Study acronym: PROCTO-CLUSTER
Active, Not Recruiting
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Summary
This retrospective, single-center observational study will use routinely collected perioperative data from adults undergoing surgery for symptomatic hemorrhoidal disease to identify data-driven clinical phenotypes. Unsupervised machine learning will be applied to characterize clusters of patients based on demographic, clinical, anatomical, and surgical variables. The study will explore whether the resulting phenotypes differ in operative complexity and postoperative course, and will generate hypotheses to inform future predictive models and personalized surgical planning.
Trial Details
NCT Number NCT07427927
Lead Sponsor IRCCS Policlinico S. Donato
Conditions Hemorrhoid, Hemorrhoid Prolapse
Enrollment 100 participants
Start Date 2024-12-01
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-04 (estimated)
Updated on ClinicalTrials.gov 2026-02-23