Project Q: Cue-based Treatment Intervention to Promote Cessation Among People Who Smoke Lightly or Non-daily

This study aims to test the feasibility and acceptability of a remotely delivered cue-based treatment intervention to promote smoking cessation among people who smoke lightly or non-daily. Secondary objectives include assessing preliminary efficacy on cessation and examining cue reactivity. Participants will be randomized to CBT only or CBT + cue-based treatment, with assessments at baseline, end-of-treatment, 6 months, and 12 months.

NCT Number	NCT07425119
Lead Sponsor	Duke University Collaborators: National Institutes of Health (NIH), National Cancer Institute (NCI), University of Oklahoma
Conditions	Tobacco Use Disorder
Enrollment	60 participants
Start Date	2026-07-07
Primary Completion	2028-01 (estimated)
Study Completion	2028-06 (estimated)
Updated on ClinicalTrials.gov	2026-07-28