BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching

Heart failure with preserved ejection fraction (HFpEF) represents a major public health burden that is both growing rapidly and has few effective therapies. Supervised exercise training (SET) is one of the few effective therapies for older patients with HFpEF, but is currently constrained by cost, resource limitations, and sub-optimal short and long-term clinical response. The objective is to develop and test novel strategies to augment the therapy of exercise training to optimize response and resource utilization in older patients with HFpEF.

NCT Number	NCT07413198
Lead Sponsor	Wake Forest University Health Sciences Collaborators: National Institute on Aging (NIA)
Conditions	Heart Failure With Preserved Ejection Fraction
Enrollment	14 participants
Start Date	2026-05-05
Primary Completion	2027-03 (estimated)
Study Completion	2027-03 (estimated)
Updated on ClinicalTrials.gov	2026-05-26