Clinical Trial

Direct vs Standard SLT for Glaucoma: A Noninferiority Trial

Recruiting
View on ClinicalTrials.gov →
Summary
This study compares two FDA-approved laser treatments for glaucoma: Direct Selective Laser Trabeculoplasty (DSLT) and Selective Laser Trabeculoplasty (SLT). Both procedures aim to lower eye pressure and prevent vision loss. DSLT is a newer, non-contact technique that may improve comfort and efficiency. Participants will be randomly assigned to receive either DSLT or SLT and followed for 12 months to assess eye pressure, safety, and treatment outcomes.
Protocol Amendment History 4 changes
critical Recruitment opened 2026-05-07
critical Phase changed: Phase 4 -> not applicable 2026-05-07
notable Primary completion pushed: 2027-04 -> 2027-10 2026-05-07
minor Completion pushed: 2027-05 -> 2027-10 2026-05-07
Trial Details
NCT Number NCT07408154
Lead Sponsor Medical University of South Carolina
Conditions Open-angle Glaucoma (OAG), Ocular Hypertension (OHT)
Enrollment 172 participants
Start Date 2026-04-27
Primary Completion 2027-10 (estimated)
Study Completion 2027-10 (estimated)
Updated on ClinicalTrials.gov 2026-05-06