Phase II, Prospective, Randomized, Proof-of-concept Study to Evaluate the Effects of a Personalized Dietary Intervention in Women With Advanced Gynecologic or Breast Tumors Treated With Antibody-Drug Conjugates (ADCs).

The objective of the study is to evaluate the effect of a personalized dietary intervention (cohort A), compared with a standard nutritional intervention based on general recommendations for following a Mediterranean diet (cohort B), in women with advanced solid tumors of gynecologic or breast origin who are receiving treatment with antibody-drug conjugates (ADCs). This intervention is exclusively nutritional and does not involve the use of any investigational drug.

NCT Number	NCT07406789
Lead Sponsor	TNC Nutrición Terapéutica S.L. Collaborators: Apices Soluciones S.L.
Conditions	Gynecologic Cancers, Advanced Breast Cancer
Enrollment	100 participants
Start Date	2026-02-11
Primary Completion	2028-02-11 (estimated)
Study Completion	2028-02-11 (estimated)
Updated on ClinicalTrials.gov	2026-02-12