Clinical Trial

Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients

Study acronym: ANKLE-DM
Not Yet Recruiting
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Summary
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery. The study will compare diabetic and non-diabetic patients and will also assess the impact of glycemic control on block onset time and postoperative analgesic consumption. Ankle block is commonly used in patients undergoing foot and ankle surgery, particularly in those with diabetes, peripheral neuropathy, or vascular disease, when general or neuraxial anesthesia may not be suitable. Previous studies suggest that diabetic neuropathy and impaired glycemic control may influence the onset and duration of peripheral nerve blocks. Adult patients scheduled for lower extremity surgery under ankle block will be included. All procedures will be performed as part of routine clinical care, and no additional interventions will be applied for research purposes. Sensory and motor block onset times, postoperative pain scores, opioid consumption within the first 24 hours, and patient and surgeon satisfaction will be recorded. The results of this study are expected to provide clinically relevant information regarding the effects of diabetes and glycemic control on ankle block characteristics and postoperative analgesia.
Trial Details
NCT Number NCT07404124
Lead Sponsor Fatih Sultan Mehmet Training and Research Hospital
Conditions Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
Enrollment 46 participants
Start Date 2026-03-01
Primary Completion 2026-10-01 (estimated)
Study Completion 2026-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-02-11