Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors

The purpose of this pilot study is to investigate the safety and preliminarily assess efficacy of early intervention with zoledronate in high risk pediatric hematopoietic stem cell transplantation (HSCT) patients to prevent the development of bone disease and fractures and reduce potential pain and suffering.

NCT Number	NCT07375290
Lead Sponsor	Children's Hospital Medical Center, Cincinnati
Conditions	Hematopoietic Stem Cell Transplantation
Enrollment	20 participants
Start Date	2026-07-17
Primary Completion	2028-01 (estimated)
Study Completion	2028-11 (estimated)
Updated on ClinicalTrials.gov	2026-08-10