Clinical Trial

Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer

Name: Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer — clinical trial record (NCT07369986)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: IMMUNE-SAVE

Not Yet Recruiting Phase 2

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Summary

Efficacy evaluate of iparomlimab and tuvonralimab (a PD-1/CTLA-4 bispecific antibody) in patients with surgically resectable dMMR endometrial cancer.

Trial Details

NCT Number	NCT07369986
Lead Sponsor	Women's Hospital School Of Medicine Zhejiang University
Conditions	Endometrial Cancer, Immunotherapy, Mismatch Repair Deficiency
Enrollment	30 participants
Start Date	2026-03-01
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-01-27