The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia

This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro). The BHPro intervention is designed to address modifiable risk factors for dementia through a 6-month, fully online, educational program conveying the best available evidence for lifestyle changes that can mitigate dementia risk, and foster engagement toward one's own brain health. Achieving lifestyle changes in a diverse Canadian population through online education would be a major achievement in dementia prevention in Canada, with widespread personal and socioeconomic benefits. Eligible participants will be randomly assigned to either start Brain Health PRO immediately or in 6 months (delayed-start control group). All participants will have the opportunity to have access to BHPro for 6 months during the course of the study and will have open access to all content for 12 months following the initial 6-month intervention. Participation will last from 18-24 months depending on group assignment.

NCT Number	NCT07364019
Lead Sponsor	University of British Columbia Collaborators: Canadian Institutes of Health Research (CIHR), Alzheimer Society of Canada, Baycrest, The Canadian Consortium on Neurodegeneration in Aging (CCNA)
Conditions	Dementia Prevention, Subjective Cognitive Impairment, Mild Cognitive Impairment, Cognitive Change, Lifestyle Intervention, Dementia Education
Enrollment	700 participants
Start Date	2026-05-07
Primary Completion	2028-12-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-19