Clinical Trial

A Clinical Study of MK-1045 in People With Lupus or Rheumatoid Arthritis (MK-1045-004)

Recruiting Phase 1
View on ClinicalTrials.gov →
Summary
This study looks at a study medicine called MK-1045 in people with lupus and rheumatoid arthritis (RA). The main goal of the study is to learn about the safety of MK-1045 and if people tolerate it when they receive it at different dose levels (amounts).
Protocol Amendment History 2 changes
notable Trial sites expanded: 12 -> 15 locations 2026-06-10
notable Trial sites expanded: 4 -> 8 locations 2026-05-05
Trial Details
NCT Number NCT07363590
Lead Sponsor Merck Sharp & Dohme LLC
Conditions Systemic Lupus Erythematosus, Rheumatoid Arthritis
Enrollment 21 participants
Start Date 2026-02-19
Primary Completion 2029-07-16 (estimated)
Study Completion 2029-07-16 (estimated)
Updated on ClinicalTrials.gov 2026-07-31