Clinical Trial

A Clinical Trial to Investigate the Safety and Efficacy of MB-1 on Metabolic Health in Overweight and Obese Adults

Not Yet Recruiting

Summary

The goal of this clinical trial is to investigate the safety and efficacy of MB-1 on metabolic health in overweight and obese adults. The main question it aims to answer is: What is the difference in change in body weight from baseline at Day 84 between MB-1 and placebo? Participants will be provided MB-1 or placebo and be assessed for anthropometric measurements, blood pressure, heart rate, and asked to complete appetite and satiety questionnaires and undergo a DEXA scan.

Protocol Amendment History 4 changes

critical Primary endpoint(s) modified 2026-07-01

notable Enrollment increased: 100 -> 120 participants 2026-07-01

notable Primary completion pushed: 2026-04 -> 2027-01 2026-07-01

minor Completion pushed: 2026-07 -> 2027-01 2026-07-01

Trial Details

NCT Number	NCT07363148
Lead Sponsor	Arrae Collaborators: KGK Science Inc.
Conditions	Obese, Overweight Adults, Obese Adults, Body Weight Control, BMI
Enrollment	120 participants
Start Date	2026-08
Primary Completion	2027-01 (estimated)
Study Completion	2027-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-30