Clear Cell Chondrosarcoma in Italy

Clear cell chondrosarcoma of bone is considered a low-grade malignant tumor in the last WHO classification of soft tissue and bone tumors; however, it is reported that recurrences and metastasis can occur. Considering the uncertain prognosis of this rare tumor, with some cases that historically seems to pursue a bad prognosis, we decided to collect all the Italian cases of clear cell condrosarcoma, in order to better understand its natural history and prognosis.

NCT Number	NCT07360964
Lead Sponsor	Istituto Ortopedico Rizzoli Collaborators: Azienda Ospedaliero, Universitaria Pisana, Gaetano Pini CTO, Milano, IRCCS Humanitas Research Hospital, Milano, Istituto Nazionale Tumori IRCCS - Fondazione G. Pascale, Ospedale "Morgagni - Pierantoni" di Forlì, A.O.U. Città della Salute e della Scienza, Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Conditions	Chondrosarcoma
Enrollment	77 participants
Start Date	2025-09-10
Primary Completion	2025-12-31 (estimated)
Study Completion	2026-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-01-22