Thermal Measurements of the Gut With a Colonoscope Compatible Thermal Probe

The goal of this clinical trial is to use a modified thermal probe to measure temperature rise in the colonic mucosa of participants with inflammatory bowel disease, Crohn's disease, and/or ulcerative colitis. The main question it aims to answer is: Is the thermal probe an effective device to use to detect temperature rise in the colonic mucosa? During the participant's standard of care colonoscopy, the thermal probe will be inserted into the colonoscope. The thermal probe is connected to a temperature transmitter that collects and saves the temperature of the colon in real time.

NCT Number	NCT07352995
Lead Sponsor	Massachusetts General Hospital Collaborators: The Leona M. and Harry B. Helmsley Charitable Trust
Conditions	Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
Enrollment	20 participants
Start Date	2026-03-25
Primary Completion	2028-12 (estimated)
Study Completion	2029-12 (estimated)
Updated on ClinicalTrials.gov	2026-04-20