WELL-MPN: A Digital Lifestyle App for Patients With MPNs

The goal of this clinical trial is to learn whether a digital lifestyle app can help improve diet, physical activity, symptoms, emotional well-being, and quality of life in adults with myeloproliferative neoplasms (MPNs). The main questions it aims to answer are: Can people with MPNs use the WELL-MPN app? Does using the WELL-MPN app improve diet quality and physical activity? Does the WELL-MPN app improve MPN-related symptoms, anxiety and depression, confidence in managing health, and overall quality of life? Researchers will compare participants who use the WELL-MPN digital app with participants who receive written educational materials about diet and physical activity for people with cancer to see if the app leads to greater improvements in lifestyle behaviors, symptoms, and well-being. Participants will: Be randomly assigned to use the WELL-MPN app or receive written lifestyle education materials Use the assigned program or materials over the study period Complete surveys about diet, physical activity, symptoms, mood, confidence in self-care, and quality of life

NCT Number	NCT07349134
Lead Sponsor	Brigham and Women's Hospital
Conditions	Myeloproliferative Neoplasms (MPNs)
Enrollment	75 participants
Start Date	2026-06
Primary Completion	2029-01 (estimated)
Study Completion	2029-06 (estimated)
Updated on ClinicalTrials.gov	2026-01-20