Clinical Trial

Clinical Efficacy of Transarterial Infusion Chemotherapy for Unresectable Colorectal Cancer

Recruiting
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Summary
This is a prospective, multicenter, randomized, open-label clinical trial. It aims to investigate whether intensive transarterial infusion chemotherapy (TAIC) followed by sequential intravenous chemotherapy (IVC) is clinically more effective than IVC alone in the treatment of unresectable colorectal cancer (uCRC).
Protocol Amendment History 2 changes
critical Primary endpoint(s) modified 2026-08-15
notable Enrollment increased: 30 -> 50 participants 2026-08-15
Trial Details
NCT Number NCT07333053
Lead Sponsor Quanda Liu
Collaborators: Liaoning Cancer Hospital & Institute, The Rocket Force Characteristic Medical Center, Second Affiliated Hospital of Nanchang University, Affiliated Hospital of Hebei University, The First Hospital of Qinhuangdao, The Central Hospital of Handan City, The First People's Hospital of Jiujiang City, Changzhi Medical College, Zibo Boshan District Traditional Chinese Medicine Hospital, Hebei Yixian Hospital, Baoding Mancheng District People's Hospital, The Shanghai Yangpu Central Hospital
Conditions Unresectable Colorectal Cancer
Enrollment 50 participants
Start Date 2026-03-20
Primary Completion 2027-12-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-08-14