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First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion

StatusRecruiting
PhasePhase 1/2
SponsorGang Hou
Started
View on ClinicalTrials.gov ↗

Record History

  1. Recruitment opened
    • Start date changed from estimate of Jan 20, 2026 to Apr 24, 2026
    • Site details revised
    v3
  2. Secondary endpoints: details revised at 1 of 5 entriesv2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study aims to evaluate the safety of intrapleural injection of TolueneSulfonamide in patients with malignant pleural effusion and to explore its potential effectiveness.
Trial Details
NCT Number NCT07332858
Lead Sponsor Gang Hou
Collaborators: The Second Affiliated Hospital of Harbin Medical University, The Affiliated Hospital of Xuzhou Medical University, Anhui Chest Hospital
Conditions
(from sponsor)		 Malignant Pleural Effusions (Mpe), Non Small Cell Lung Cancer
Related terms Carcinoma, Non-Small-Cell Lung, Myeloproliferative Disorder, Chronic, with Eosinophilia, Pleural Effusion, Malignant
Enrollment 105 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov